Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890314 | 0.87 | EPHX2 (0.55) | PARP10SRD5A1EPHX2HRH3 | |
| SCHEMBL14412821 | 0.87 | EPHX2 (0.57) | SRD5A1EPHX2 | |
| SCHEMBL213590 | 0.87 | SRD5A1 (0.50) | PARP10SRD5A1SRD5A2KMT2AEPHX2 | |
| SCHEMBL14413606 | 0.86 | SRD5A1 (0.64) | PARP10SRD5A1SRD5A2KMT2AEPHX2 | |
| SCHEMBL9013886 | 0.85 | CASP6 (0.53) | PARP10SRD5A1SRD5A2KMT2AHRH3 | |
| SCHEMBL4603682 | 0.84 | LMNA (0.55) | KMT2AHRH3POLB | |
| Hydrochloric Acid SCHEMBL9014030 | 0.84 | CASP6 (0.51) | PARP10SRD5A1SRD5A2KMT2AHRH3 | |
| SCHEMBL3222147 | 0.83 | EPHX2 (0.58) | PARP10SRD5A1EPHX2HRH3 | |
| SCHEMBL14413534 | 0.82 | GPR119 (0.63) | EPHX2HRH3GPR119 | |
| SCHEMBL21814302 | 0.81 | NAMPT (0.59) | KMT2AHRH3ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |