Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014050 | 0.87 | NAMPT (0.41) | CTSLCTSSCTSKHRH3NAMPT | |
| Fumaric Acid SCHEMBL9013969 | 0.79 | HRH1 (0.47) | CTSLCTSSCTSK | |
| Fumaric Acid SCHEMBL9013959 | 0.79 | HRH1 (0.47) | CTSLCTSSCTSK | |
| SCHEMBL9014079 | 0.72 | HRH3 (0.43) | HRH3 | |
| SCHEMBL9013972 | 0.72 | HRH3 (0.41) | LMNAHRH3 | |
| SCHEMBL9013850 | 0.70 | NAMPT (0.49) | LMNAHRH3NAMPT | |
| SCHEMBL9013798 | 0.69 | FFAR4 (0.44) | HRH3NAMPT | |
| SCHEMBL9014068 | 0.69 | HRH3 (0.41) | HRH3 | |
| SCHEMBL9013895 | 0.68 | KMT2A (0.38) | HRH3 | |
| SCHEMBL9013888 | 0.68 | FFAR4 (0.42) | HRH3NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |