Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.44 |
| ▸ | ACACB | O00763 | 9/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013888 | 0.90 | FFAR4 (0.42) | FFAR4ACACBNAMPTHRH3 | |
| SCHEMBL9014033 | 0.82 | PARP15 (0.42) | FFAR4ACACBPARP10 | |
| SCHEMBL9013972 | 0.78 | HRH3 (0.41) | ACACBHRH1HRH3CCR3 | |
| SCHEMBL9014134 | 0.78 | CASP6 (0.51) | FFAR4ACACBNAMPTHRH1HRH3 | |
| SCHEMBL20000474 | 0.77 | L3MBTL1 (0.47) | FFAR4ACACBHRH3PARP10KCNH2 | |
| SCHEMBL20000543 | 0.77 | PARP10 (0.47) | FFAR4ACACBHRH1HRH3PARP10 | |
| Fumaric Acid SCHEMBL9013794 | 0.76 | HRH1 (0.51) | FFAR4ACACBPTGS2NAMPTHRH1 | |
| Fumaric Acid SCHEMBL9013804 | 0.76 | HRH1 (0.51) | FFAR4ACACBPTGS2NAMPTHRH1 | |
| SCHEMBL3038638 | 0.76 | ALDH1A1 (0.50) | FFAR4ACACBHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL9013866 | 0.74 | NAMPT (0.48) | ACACBNAMPTHRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |