Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068839 | 0.88 | TSHR (0.51) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2186773 | 0.86 | MEN1 (0.42) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8671212 | 0.85 | TSHR (0.59) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3478112 | 0.85 | TSHR (0.59) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL28249903 | 0.84 | MEN1 (0.44) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16387622 | 0.83 | MEN1 (0.43) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL1355836 | 0.81 | TSHR (0.51) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL29561089 | 0.81 | TSHR (0.51) | TSHRALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL28036070 | 0.81 | ALDH1A1 (0.43) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3948593 | 0.81 | GRIN2D (0.45) | TSHRMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779123-A | Fused tetracyclic compound, its composition and purposes | 泰博生物科技有限公司 | 2018-11-09 | — | — | CN | disclosed |
| US-5482719-A | Drug delivery systems | MEDIPRO SCIENCES LIMITED (CA) | 1996-01-09 | — | — | US | disclosed |
| WO-1994009826-A2 | DRUG DELIVERY SYSTEMS, CHARACTERISED BY A PHOTOLABILE LINKAGE | MEDIPRO SCIENCES LIMITED (CA) | 1994-05-11 | — | — | WO | disclosed |