Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16532712 | 0.92 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2CYP2D6KMT2A | |
| SCHEMBL16823039 | 0.92 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2CYP2D6KMT2A | |
| SCHEMBL6136613 | 0.87 | CYP1A2 (0.50) | ALDH1A1HPGDCYP1A2CYP2D6KMT2A | |
| SCHEMBL9014151 | 0.84 | SLC6A2 (0.55) | ALDH1A1HPGDMAPTPOLBLMNA | |
| SCHEMBL596980 | 0.83 | GPR119 (0.64) | ALDH1A1CYP1A2CYP2D6MAPTCHEK2 | |
| SCHEMBL21814304 | 0.83 | KMT2A (0.62) | CYP1A2CYP2D6KMT2AMAPTNAMPT | |
| SCHEMBL3274096 | 0.82 | HRH3 (0.55) | ALDH1A1HPGDMAPTEPHX2POLB | |
| SCHEMBL21814290 | 0.82 | KMT2A (0.53) | CYP1A2CYP2D6KMT2AMAPTNAMPT | |
| SCHEMBL3575478 | 0.82 | CYP1A2 (0.48) | ALDH1A1HPGDCYP1A2CYP2D6KMT2A | |
| SCHEMBL1863827 | 0.82 | CYP1A2 (0.48) | ALDH1A1HPGDCYP1A2CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5254689-A | Antiarrhythmia agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |
| US-5202346-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |