Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.51 |
| ▸ | ITGAL | P20701 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481721 | 0.89 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRNB4 | |
| SCHEMBL2481879 | 0.85 | GPR119 (0.53) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL29796085 | 0.85 | GPR119 (0.53) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL374672 | 0.84 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL9014017 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTPOLBHPGDLMNA | |
| SCHEMBL22735334 | 0.84 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRNB4 | |
| SCHEMBL4707629 | 0.84 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRNB4 | |
| SCHEMBL29739455 | 0.82 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRNB4 | |
| SCHEMBL19878954 | 0.82 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRNB4 | |
| SCHEMBL30996465 | 0.81 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |