Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014274 | 0.85 | PTGIR (0.55) | PTGIRPTGDRSIGMAR1 | |
| SCHEMBL9014427 | 0.83 | PTGIR (0.55) | PTGIRPTGDRSIGMAR1 | |
| SCHEMBL9014489 | 0.80 | PTGIR (0.58) | PTGIRPTGDRSIGMAR1 | |
| SCHEMBL9014493 | 0.79 | PTGIR (0.39) | PTGIRPTGDR | |
| SCHEMBL9014499 | 0.79 | PTGIR (0.39) | PTGIRPTGDR | |
| SCHEMBL9014581 | 0.78 | PTGIR (0.58) | PTGIRPTGDRSIGMAR1 | |
| SCHEMBL9014460 | 0.77 | PTGIR (0.69) | PTGIRPTGDRSIGMAR1DDB1CRBN | |
| SCHEMBL9014450 | 0.77 | PTGIR (0.69) | PTGIRPTGDRSIGMAR1DDB1CRBN | |
| SCHEMBL9014231 | 0.77 | PTGIR (0.57) | PTGIRSIGMAR1 | |
| SCHEMBL8858542 | 0.76 | PTGIR (0.58) | PTGIRPTGDRSIGMAR1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |