Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014499 | 1.00 | PTGIR (0.39) | PTGIRPPARGPPARDPTGDRMRGPRX4 | |
| SCHEMBL9014215 | 0.85 | TBXAS1 (0.39) | PTGIR | |
| SCHEMBL9014217 | 0.85 | TBXAS1 (0.39) | PTGIR | |
| SCHEMBL9014438 | 0.84 | TBXAS1 (0.41) | PTGIRPPARGPPARD | |
| SCHEMBL9014441 | 0.84 | TBXAS1 (0.41) | PTGIRPPARGPPARD | |
| SCHEMBL9014512 | 0.80 | PTGIR (0.40) | PTGIRPTGDR | |
| SCHEMBL9014522 | 0.80 | PTGIR (0.40) | PTGIRPTGDR | |
| SCHEMBL9014633 | 0.80 | PTGIR (0.45) | PTGIR | |
| SCHEMBL9014629 | 0.80 | PTGIR (0.45) | PTGIR | |
| SCHEMBL9014200 | 0.79 | PTGIR (0.55) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |