Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014427 | 0.95 | PTGIR (0.55) | PTGIRPTGDRKMT2ATBXAS1MAPK1 | |
| SCHEMBL9014581 | 0.89 | PTGIR (0.58) | PTGIRPTGDRKMT2ATBXAS1MAPK1 | |
| SCHEMBL9014200 | 0.85 | PTGIR (0.55) | PTGIRPTGDRSIGMAR1 | |
| SCHEMBL9014489 | 0.84 | PTGIR (0.58) | PTGIRPTGDRTBXAS1SIGMAR1 | |
| SCHEMBL9014666 | 0.84 | PTGIR (0.51) | PTGIRPTGDRTBXAS1GPR132 | |
| SCHEMBL9014447 | 0.84 | PTGIR (0.51) | PTGIRPTGDRKMT2ATBXAS1SIGMAR1 | |
| SCHEMBL9085150 | 0.83 | PTGIR (0.51) | PTGIRPTGDRTBXAS1 | |
| SCHEMBL9014215 | 0.79 | TBXAS1 (0.39) | PTGIRKMT2ATBXAS1MAPK1HTT | |
| SCHEMBL9014217 | 0.79 | TBXAS1 (0.39) | PTGIRKMT2ATBXAS1MAPK1HTT | |
| SCHEMBL9014462 | 0.78 | TBXAS1 (0.60) | PTGIRTBXAS1MAPK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |