Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014205 | 1.00 | PTGIR (0.54) | PTGIRTBXAS1PTGDRTDP1TBXA2R | |
| SCHEMBL9014275 | 0.92 | TBXAS1 (0.57) | PTGIRTBXAS1PTGDRTBXA2R | |
| SCHEMBL9014272 | 0.92 | TBXAS1 (0.57) | PTGIRTBXAS1PTGDRTBXA2R | |
| SCHEMBL9014267 | 0.82 | TBXAS1 (0.45) | PTGIRTBXAS1PTGDRALDH1A1 | |
| SCHEMBL9014457 | 0.82 | TBXAS1 (0.45) | PTGIRTBXAS1PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL9014467 | 0.82 | TBXAS1 (0.45) | PTGIRTBXAS1PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL9014270 | 0.82 | TBXAS1 (0.45) | PTGIRTBXAS1PTGDRALDH1A1 | |
| SCHEMBL9014551 | 0.80 | PTGIR (0.54) | PTGIRTBXAS1PTGDRTDP1TBXA2R | |
| SCHEMBL9014546 | 0.80 | PTGIR (0.54) | PTGIRTBXAS1PTGDRTDP1TBXA2R | |
| SCHEMBL9014210 | 0.80 | TBXAS1 (0.48) | PTGIRTBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |