Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | FHIT | P49789 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848706 | 0.70 | TSHR (0.40) | TSHRFHITSIRT2GAATDP1 | |
| SCHEMBL9014348 | 0.70 | TSHR (0.36) | TSHRSIRT2TDP1ALDH1A1LMNA | |
| SCHEMBL22754195 | 0.69 | TSHR (0.43) | TSHRFHITSIRT2GAATDP1 | |
| SCHEMBL9511515 | 0.69 | TSHR (0.50) | TSHRPTGER2PTGER4PTGER3SIRT2 | |
| SCHEMBL9013962 | 0.68 | TSHR (0.38) | TSHRFHITSIRT2TDP1ALDH1A1 | |
| SCHEMBL5896745 | 0.66 | CYP1A2 (0.38) | GAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10614279 | 0.65 | TSHR (0.46) | TSHRPTGER2SIRT2TDP1ALDH1A1 | |
| SCHEMBL11760611 | 0.65 | PTGER2 (0.52) | TSHRPTGER2PTGER4PTGER3TDP1 | |
| SCHEMBL9565118 | 0.65 | TSHR (0.38) | TSHRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL9509126 | 0.64 | BRD4 (0.44) | TSHRGAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533378-B1 | Process for producing octahydrocoumarin or derivative thereof | SUMITOMO CHEMICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0551019-A1 | Catalytic process of producing coumarin and derivatives thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-07-14 | — | — | EP | disclosed |
| EP-0533378-A1 | Process for producing octahydrocoumarin or derivative thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-24 | — | — | EP | disclosed |