Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754195 | 0.75 | TSHR (0.43) | TSHRSIRT2TDP1ALDH1A1LMNA | |
| SCHEMBL13103728 | 0.73 | TSHR (0.41) | TSHRALDH1A1LMNAMAPTHTT | |
| SCHEMBL9565118 | 0.73 | TSHR (0.38) | TSHRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL10848706 | 0.72 | TSHR (0.40) | TSHRSIRT2BRD4TDP1ALDH1A1 | |
| SCHEMBL10614279 | 0.71 | TSHR (0.46) | TSHRSIRT2BRD4TDP1ALDH1A1 | |
| SCHEMBL9014269 | 0.70 | TSHR (0.34) | TSHRSIRT2TDP1ALDH1A1LMNA | |
| SCHEMBL22680909 | 0.69 | TSHR (0.33) | TSHRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL9511515 | 0.68 | TSHR (0.50) | TSHRSIRT2TDP1ALDH1A1LMNA | |
| SCHEMBL9013962 | 0.67 | TSHR (0.38) | TSHRSIRT2TDP1ALDH1A1LMNA | |
| SCHEMBL11763977 | 0.66 | NPC1 (0.54) | TSHRTDP1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533378-B1 | Process for producing octahydrocoumarin or derivative thereof | SUMITOMO CHEMICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0533378-A1 | Process for producing octahydrocoumarin or derivative thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-24 | — | — | EP | disclosed |