SCHEMBL9014404

SCHEMBL9014404

Cc1cn([C@H]2CC(ON)[C@@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.55
TK1 P04183 7/20 0.48
TK2 O00142 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446918 1.00 RNASE1 (0.55) RNASE1TK1TK2
SCHEMBL6364200 0.90 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL8377239 0.89 RNASE1 (0.54) RNASE1TK1TK2
SCHEMBL7917157 0.89 RNASE1 (0.54) RNASE1TK1TK2
SCHEMBL8189618 0.89 RNASE1 (0.52) RNASE1TK1TK2
SCHEMBL7746722 0.89 RNASE1 (0.52) RNASE1TK1TK2
SCHEMBL7743991 0.88 RNASE1 (0.54) RNASE1TK1TK2
SCHEMBL8591071 0.88 RNASE1 (0.55) RNASE1TK1TK2
SCHEMBL5489355 0.88 RNASE1 (0.53) RNASE1TK1TK2
SCHEMBL5475148 0.88 RNASE1 (0.53) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5561225-A Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages SOUTHERN RESEARCH INSTITUTE (US) 1996-10-01 US disclosed
EP-0381335-A1 Antiviral agent and novel nucleoside TANABE SEIYAKU CO., LTD. (JP) 1990-08-08 EP disclosed