Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120550 | 0.84 | FDPS (0.45) | FDPSHDAC6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL28340215 | 0.82 | FDPS (0.44) | FDPSHDAC6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL6036330 | 0.81 | CDK1 (0.44) | FDPSHSP90AA1HSP90AB1EGFR | |
| SCHEMBL3506547 | 0.80 | ADORA2A (0.46) | EGFR | |
| SCHEMBL852593 | 0.79 | HSP90AB1 (0.41) | HDAC6HSP90AA1HSP90AB1HDAC1 | |
| SCHEMBL851861 | 0.79 | FDPS (0.32) | FDPS | |
| SCHEMBL27558464 | 0.78 | FDPS (0.37) | FDPSHDAC6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL27035498 | 0.77 | HDAC6 (0.35) | FDPSHDAC6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL6434260 | 0.75 | FDPS (0.35) | FDPSHDAC6ALDH1A1HSD17B10HPGD | |
| SCHEMBL28480707 | 0.75 | CDK1 (0.47) | HDAC6ALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561225-A | Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages | SOUTHERN RESEARCH INSTITUTE (US) | 1996-10-01 | — | — | US | disclosed |