Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036330 | 0.86 | CDK1 (0.44) | FDPSCDK1CCNB1CCNE1CDK2 | |
| SCHEMBL852593 | 0.83 | HSP90AB1 (0.41) | — | |
| SCHEMBL9014630 | 0.79 | FDPS (0.36) | FDPS | |
| SCHEMBL2120550 | 0.76 | FDPS (0.45) | FDPS | |
| SCHEMBL120720 | 0.75 | ADORA2A (0.49) | — | |
| SCHEMBL28340215 | 0.75 | FDPS (0.44) | FDPS | |
| SCHEMBL523465 | 0.73 | XDH (0.47) | — | |
| SCHEMBL5607948 | 0.73 | XDH (0.31) | FDPS | |
| SCHEMBL28547400 | 0.72 | CYP1A2 (0.40) | FDPS | |
| SCHEMBL27558464 | 0.71 | FDPS (0.37) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433941-A1 | Process for isolating the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | Bristol-Myers Squibb Company (US) | 2012-03-28 | — | — | EP | disclosed |