Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983442 | 0.86 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2AHCY | |
| SCHEMBL3506547 | 0.84 | ADORA2A (0.46) | AHCYADORA2A | |
| SCHEMBL6036330 | 0.83 | CDK1 (0.44) | CDK1CCNB1CCNE1CDK2AHCY | |
| SCHEMBL6013684 | 0.77 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2AHCY | |
| SCHEMBL15789757 | 0.77 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2HDAC6 | |
| SCHEMBL27035498 | 0.76 | HDAC6 (0.35) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9014630 | 0.75 | FDPS (0.36) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL7534078 | 0.73 | CYP1A2 (0.47) | — | |
| SCHEMBL1825531 | 0.71 | XDH (0.51) | CDK1CCNB1CCNE1CDK2ALDH1A1 | |
| SCHEMBL27303515 | 0.70 | HDAC6 (0.40) | CDK1CCNB1CCNE1CDK2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111744019-B | Mannose-based mRNA targeted delivery system and application thereof | 深圳瑞吉生物科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-114929244-A | Mannose-based mRNA targeted delivery system and application thereof | 深圳市瑞吉生物科技有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-111744019-A | Mannose-based mRNA (messenger ribonucleic acid) targeted delivery system and application thereof | 深圳市瑞吉生物科技有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-117089536-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-111744019-B | Mannose-based mRNA targeted delivery system and application thereof | 深圳瑞吉生物科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-114929244-A | Mannose-based mRNA targeted delivery system and application thereof | 深圳市瑞吉生物科技有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-112005115-A | Methods of characterizing multiple analytes from a single cell or cell population | 10X基因组学有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-111744019-A | Mannose-based mRNA (messenger ribonucleic acid) targeted delivery system and application thereof | 深圳市瑞吉生物科技有限公司 | 2020-10-09 | — | — | CN | disclosed |