Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9085150 | 0.87 | PTGIR (0.51) | PTGIRPTGDRTBXAS1 | |
| SCHEMBL9014427 | 0.87 | PTGIR (0.55) | PTGIRPTGDRTBXAS1ITGB3ITGAV | |
| SCHEMBL9014581 | 0.86 | PTGIR (0.58) | PTGIRPTGDRTBXAS1 | |
| SCHEMBL9014447 | 0.85 | PTGIR (0.51) | PTGIRPTGDRTBXAS1 | |
| SCHEMBL9014274 | 0.84 | PTGIR (0.55) | PTGIRPTGDRTBXAS1GPR132 | |
| SCHEMBL9014306 | 0.81 | TBXAS1 (0.43) | PTGIRTBXAS1ITGB3ITGAV | |
| SCHEMBL9014311 | 0.81 | TBXAS1 (0.43) | PTGIRTBXAS1ITGB3ITGAV | |
| SCHEMBL9014182 | 0.81 | TBXAS1 (0.58) | PTGIRTBXAS1 | |
| SCHEMBL9014489 | 0.81 | PTGIR (0.58) | PTGIRPTGDRTBXAS1 | |
| SCHEMBL9014224 | 0.77 | PTGIR (0.62) | PTGIRPTGDRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |