Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014427 | 0.87 | PTGIR (0.55) | PTGIRPTGDRTBXAS1KMT2ASIGMAR1 | |
| SCHEMBL9014581 | 0.86 | PTGIR (0.58) | PTGIRPTGDRTBXAS1KMT2ASIGMAR1 | |
| SCHEMBL9014666 | 0.85 | PTGIR (0.51) | PTGIRPTGDRTBXAS1 | |
| SCHEMBL9014274 | 0.84 | PTGIR (0.55) | PTGIRPTGDRTBXAS1KMT2ASIGMAR1 | |
| SCHEMBL9085150 | 0.81 | PTGIR (0.51) | PTGIRPTGDRTBXAS1 | |
| SCHEMBL9014489 | 0.81 | PTGIR (0.58) | PTGIRPTGDRTBXAS1SIGMAR1 | |
| SCHEMBL9014294 | 0.80 | TBXAS1 (0.40) | PTGIRPTGDRTBXAS1PTGDR2PTGER1 | |
| SCHEMBL9014287 | 0.80 | TBXAS1 (0.40) | PTGIRPTGDRTBXAS1PTGDR2PTGER1 | |
| SCHEMBL9014331 | 0.79 | PTGIR (0.58) | PTGIRPTGDRTBXAS1PTGER1PTGER2 | |
| SCHEMBL9014440 | 0.77 | PTGIR (0.62) | PTGIRPTGDRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |