Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880357 | 0.82 | KDM4E (0.48) | KDM4EACHEALDH1A1MAPTNPC1 | |
| SCHEMBL30681964 | 0.81 | KDM4E (0.47) | KDM4EACHEALDH1A1MAPTNPC1 | |
| SCHEMBL26617701 | 0.81 | KDM4E (0.47) | KDM4EACHEALDH1A1MAPTNPC1 | |
| SCHEMBL26617997 | 0.79 | KDM4E (0.46) | KDM4EACHEALDH1A1MAPTNPC1 | |
| SCHEMBL31345638 | 0.79 | KDM4E (0.46) | KDM4EACHEALDH1A1MAPTNPC1 | |
| SCHEMBL16116185 | 0.75 | ACHE (0.44) | KDM4EACHEALDH1A1MAPTALOX15 | |
| SCHEMBL7543209 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1CYP1A2HPGD | |
| SCHEMBL2023364 | 0.72 | L3MBTL1 (0.49) | KDM4EALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL22021573 | 0.72 | ACHE (0.47) | KDM4EACHEALDH1A1MAPTCYP1A2 | |
| SCHEMBL10563413 | 0.72 | KDM4E (0.73) | KDM4EACHEALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578596-A | TREATMENT OF SEROTONERGIC NEURON RELATED DISEASES, MOTION SICKNESS, ANXIXETY, DEPRESSION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-11-26 | — | — | US | disclosed |