Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 8/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637650 | 0.93 | PTGS2 (0.56) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8639798 | 0.92 | PTGS2 (0.66) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8637676 | 0.91 | PTGS2 (0.56) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8639018 | 0.90 | PTGS2 (0.55) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8644125 | 0.90 | PTGS2 (0.51) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8637364 | 0.88 | PTGS2 (0.53) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8640280 | 0.87 | PTGS2 (0.52) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8637296 | 0.86 | PTGS2 (0.48) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8643884 | 0.84 | PTGS2 (0.53) | PTGS2PTGS1PDPK1RXRANR1H2 | |
| SCHEMBL8639194 | 0.83 | PTGS2 (0.46) | PTGS2PTGS1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510496-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |