Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693129 | 0.79 | CYP1A2 (0.54) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL4690968 | 0.78 | KDM4E (0.55) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL5464541 | 0.74 | ALDH1A1 (0.49) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL4094385 | 0.73 | L3MBTL1 (0.50) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL2290451 | 0.73 | CYP3A4 (0.56) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL7425880 | 0.73 | CYP3A4 (0.52) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL10556236 | 0.71 | MEN1 (0.55) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL2325918 | 0.71 | L3MBTL1 (0.80) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL14276933 | 0.71 | CYP3A4 (0.66) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL10338948 | 0.70 | CYP3A4 (0.74) | L3MBTL1CYP1A2CYP3A4CYP2D6BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041934-A1 | POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | disclosed |