Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000509 | 0.83 | HSD11B1 (0.48) | ENPP2HSD11B1KDM4E | |
| SCHEMBL21457575 | 0.83 | HSD11B1 (0.48) | ENPP2HSD11B1KDM4E | |
| SCHEMBL26709208 | 0.79 | MEN1 (0.33) | ENPP2HSD11B1KDM4E | |
| SCHEMBL10383610 | 0.75 | KDM4E (0.40) | ENPP2KDM4E | |
| SCHEMBL29047693 | 0.74 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL16933971 | 0.69 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL297693 | 0.69 | NFE2L2 (0.50) | HSD11B1 | |
| SCHEMBL11813801 | 0.69 | CDK4 (0.48) | HSD11B1KDM4E | |
| SCHEMBL16933968 | 0.69 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL4951414 | 0.69 | NFE2L2 (0.50) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |