SCHEMBL297693

SCHEMBL297693

Brc1cccc(C=Cc2ccccc2)c1Br

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.50
TRPA1 O75762 2/20 0.50
MAOB P27338 3/20 0.41
CYP19A1 P11511 2/20 0.41
MAOA P21397 2/20 0.41
DHFR P00374 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GRM4 Q14833 1/20 0.39
EGFR P00533 1/20 0.39
PTPN1 P18031 1/20 0.39
HSD11B1 P28845 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951414 1.00 NFE2L2 (0.50) NFE2L2TRPA1MAOBCYP19A1MAOA
Anisole SCHEMBL29005803 0.87 TRPA1 (0.56) NFE2L2TRPA1MEN1KMT2A
SCHEMBL6737776 0.85 NFE2L2 (0.56) NFE2L2TRPA1MAOBCYP19A1MAOA
SCHEMBL14703725 0.85 NFE2L2 (0.56) NFE2L2TRPA1MAOBCYP19A1MAOA
SCHEMBL6737772 0.85 NFE2L2 (0.56) NFE2L2TRPA1MAOBCYP19A1MAOA
SCHEMBL30364986 0.85 NFE2L2 (0.56) NFE2L2TRPA1MAOBCYP19A1MAOA
SCHEMBL29054340 0.83 NFE2L2 (0.45) NFE2L2TRPA1MAOBCYP19A1MAOA
SCHEMBL29047693 0.80 HSD11B1 (0.42) NFE2L2MAOBMEN1KMT2AHSD11B1
SCHEMBL29627775 0.80 NFE2L2 (0.47) NFE2L2TRPA1MAOBCYP19A1MAOA
SCHEMBL29627779 0.80 NFE2L2 (0.47) NFE2L2TRPA1MAOBCYP19A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111039920-B Chiral tetraphenylethylene and synthesis method thereof 山东大学 2021-01-12 CN claimed
CN-111039920-A Chiral tetraphenylethylene and synthesis method thereof 山东大学 2020-04-21 CN claimed
JP-7133284-A None JP disclosed
EP-3527593-B1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-23 EP disclosed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
CN-114957128-B Diaryl imidazolium salt and antibacterial application thereof 四川大学 2024-07-23 CN disclosed
CN-112979917-B Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2023-04-25 CN disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
CN-109790269-B Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2022-06-14 CN disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4568705-A HIGH RESILIENT POLYETHER-AND ESTERURETHANES BASF WYANDOTTE CORPORATION (US) 1986-02-04 US disclosed
EP-0163188-A2 A graft polymer dispersion in a mixture of low molecular weight polyols and polyether polyols and polyurethane foams prepared therefrom BASF Corporation (US) 1985-12-04 EP disclosed
US-4555527-A POLYURETHANE FOAM BASF WYANDOTTE CORPORATION (US) 1985-11-26 US disclosed
US-4522976-A Graft polymer dispersion in a mixture of low molecular weight polyols and polyether polyols and polyurethane foams prepared therefrom BASF WYANDOTTE CORPORATION (US) 1985-06-11 US disclosed
US-4503207-A UNSATURATION-CONTAINING POLYOLS BASF WYANDOTTE CORPORATION (US) 1985-03-05 US disclosed
US-4458038-A ADDITION-CONDENSATION COPOLYMERS BASF WYANDOTTE CORPORATION (US) 1984-07-03 US disclosed
US-4454255-A 0.001 TO 0.09 MOLE OF INDUCED UNSATURATION PER MOLE OF POLYOL MIXTURE BASF WYANDOTTE CORPORATION (US) 1984-06-12 US disclosed
EP-0091036-A2 Process for the preparation of white graft polymer dispersions and flame-retardant polyurethane foams BASF Corporation (US) 1983-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B NFE2L2 1131/4885TRPA1 899/4885MAOB 2543/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B NFE2L2 1150/4885TRPA1 953/4885MAOB 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.