Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026125 | 0.87 | LMNA (0.65) | LMNAMAPK1CES2CES1 | |
| SCHEMBL159419 | 0.87 | LMNA (0.65) | LMNAMAPK1CES2CES1 | |
| SCHEMBL4136525 | 0.87 | LMNA (0.65) | LMNAMAPK1CES2CES1 | |
| Water SCHEMBL28741444 | 0.85 | LMNA (0.62) | LMNAMAPK1CES2CES1 | |
| Hydrochloric Acid SCHEMBL8893721 | 0.85 | LMNA (0.62) | LMNAMAPK1CES2CES1 | |
| SCHEMBL7564021 | 0.83 | LMNA (0.74) | PTGS2LMNAMAPK1ACP3CES2 | |
| SCHEMBL8993579 | 0.83 | LMNA (0.74) | PTGS2LMNAMAPK1ACP3CES2 | |
| SCHEMBL7564005 | 0.83 | LMNA (0.74) | PTGS2LMNAMAPK1ACP3CES2 | |
| SCHEMBL7193261 | 0.79 | PTGS2 (0.52) | PTGS2ACP3CHRNB2CHRNA4DHODH | |
| SCHEMBL30785017 | 0.79 | PTGS2 (0.57) | PTGS2LMNAMAPK1ACP3CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746551-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-12-11 | — | — | EP | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |