Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116132 | 0.81 | ADH1B (0.40) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL5285758 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL8604355 | 0.78 | CYP1A2 (0.41) | — | |
| SCHEMBL7595079 | 0.77 | CA2 (0.36) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL15973931 | 0.77 | — | — | |
| SCHEMBL4936168 | 0.76 | ADH1B (0.36) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL570529 | 0.76 | TSHR (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL25211388 | 0.75 | ADH1B (0.42) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL28600523 | 0.74 | ADH1B (0.47) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL11251404 | 0.72 | TRPA1 (0.44) | TSHRSMN1; SMN2ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746551-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-12-11 | — | — | EP | disclosed |