Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL2168299 | 0.96 | HCAR2 (0.58) | HCAR2ATMTSHRHPGDHRH1 | |
| Ethyl Fumarate SCHEMBL2705043 | 0.90 | HCAR2 (0.62) | HCAR2ATMTSHRHPGDHRH1 | |
| Alcohol SCHEMBL10901489 | 0.85 | HCAR2 (0.47) | HCAR2ATMHRH1EPHX1NAAA | |
| Acrylic Acid Methyl Ester SCHEMBL11282822 | 0.84 | HCAR2 (0.48) | HCAR2ATMHRH1EPHX1ALDH1A1 | |
| Fumaric Acid SCHEMBL9862115 | 0.83 | ATM (0.38) | HCAR2ATMTSHRHRH1EPHX1 | |
| Acrylic Acid Ethyl Ester SCHEMBL2271601 | 0.83 | TSHR (0.46) | HCAR2TSHRHPGDEPHX1ALDH1A1 | |
| Maleic Acid SCHEMBL5417329 | 0.83 | ATM (0.38) | HCAR2ATMTSHRHRH1EPHX1 | |
| SCHEMBL9400666 | 0.82 | MAPT (0.41) | HCAR2ATMTSHRHPGDHRH1 | |
| SCHEMBL28757795 | 0.81 | HCAR2 (0.52) | HCAR2ATMEPHX1NAAAALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL15318875 | 0.81 | HCAR2 (0.54) | HCAR2ATMTSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746509-A1 | CONTAINER CLOSURE HAVING AN IMPROVED SEALING LINER | ALCOA CLOSURE SYSTEMS INTERNATIONAL, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1996020879-A2 | CONTAINER CLOSURE HAVING AN IMPROVED SEALING LINER | ALCOA CLOSURE SYSTEMS INTERNATIONAL, INC. (US) | 1996-07-11 | — | — | WO | disclosed |