Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405439 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL874531 | 0.93 | ALDH1A1 (0.47) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL9508794 | 0.92 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL9508798 | 0.92 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| Ammonia Solution, Strong SCHEMBL27937161 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL9510203 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL10405802 | 0.86 | TDP1 (0.46) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL2128463 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2ATHRB | |
| SCHEMBL9215261 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNACYP3A4MEN1USP2 | |
| SCHEMBL9512255 | 0.85 | ACACB (0.45) | ALDH1A1LMNACYP3A4MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541334-A | TREATING HIV | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |