Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27937161 | 0.98 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL9015403 | 0.93 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL10405439 | 0.93 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL9512255 | 0.92 | ACACB (0.45) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL2128463 | 0.88 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9510203 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL9508798 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL9508794 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL16933991 | 0.84 | LMNA (0.62) | ALDH1A1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL19003536 | 0.83 | LMNA (0.58) | ALDH1A1LMNAMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471355-B | Diphenyl sulfide derivatives and drugs containing the same as the active ingredient | KYORIN PHARMACEUTICAL CO.,LTD. (JP) | 2015-10-07 | — | — | CN | disclosed |
| EP-2619184-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | The Regents of the University of Michigan (US) | 2013-07-31 | — | — | EP | disclosed |
| CN-102471355-A | Diphenyl sulfide derivatives and drugs containing the same as the active ingredient | KYORIN SEIYAKU KK | 2012-05-23 | — | — | CN | disclosed |
| WO-2012040527-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | WO | disclosed |
| US-4853150-A | 2-(4,3-Disubstituted phenyl)-5-alkyl-1,3,2-dioxaborinane derivatives and liquid crystal material | NAUCHNO-ISSLEDOVATELSKY INSTITUT PRIKLADNYKH FIZICHESKIKH PROBLEM IMENI A. N. SEVCHENKO (SU) | 1989-08-01 | — | — | US | disclosed |