SCHEMBL9015628

SCHEMBL9015628

CCCCCCSCC(=O)Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.67
TP53 P04637 2/20 0.67
GMNN O75496 1/20 0.67
POLB P06746 1/20 0.67
MAPT P10636 1/20 0.67
THRB P10828 1/20 0.67
CYP2C9 P11712 1/20 0.67
BLM P54132 1/20 0.67
HSD17B10 Q99714 1/20 0.67
CES1 P23141 8/20 0.58
FAAH O00519 4/20 0.58
PLA2G6 O60733 1/20 0.58
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
CA2 P00918 1/20 0.44
EPHX1 P07099 1/20 0.41
PLA2G4B P0C869 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
GPR84 Q9NQS5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10401245 0.91
SCHEMBL11144140 0.86 CES2 (0.44) CES2TP53GMNNPOLBMAPT
SCHEMBL9857458 0.81
SCHEMBL7743848 0.81 TSHR (0.75) CES2TP53GMNNPOLBMAPT
SCHEMBL9050797 0.81 TSHR (0.61) CES2TP53GMNNPOLBMAPT
SCHEMBL9015601 0.81 TSHR (0.61) CES2TP53GMNNPOLBMAPT
SCHEMBL7749088 0.81 TSHR (0.75) CES2TP53GMNNPOLBMAPT
SCHEMBL8624811 0.81 TSHR (0.61) CES2TP53GMNNPOLBMAPT
SCHEMBL8464950 0.81 TSHR (0.75) CES2TP53GMNNPOLBMAPT
SCHEMBL9015611 0.81 TSHR (0.61) CES2TP53GMNNPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5516856-A IMPROVED PROCESS FOR THE MODIFICATION OF THE MOLECULAR CHAIN OF A POLYMER ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-05-14 US disclosed
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 US disclosed
US-5051531-A As polymerization catalysts and for crosslinking ATOCHEM NORTH AMERICA, INC. (US) 1991-09-24 US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 US disclosed
EP-0344733-A2 Novel antioxidant-peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-12-06 EP disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 EP disclosed