Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072709 | 0.82 | TSHR (0.34) | LMNA | |
| SCHEMBL8616662 | 0.81 | — | — | |
| SCHEMBL27338300 | 0.81 | ALDH1A1 (0.43) | LMNA | |
| SCHEMBL9015803 | 0.80 | HSD17B10 (0.37) | LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL24407989 | 0.79 | EGLN1 (0.39) | LMNA | |
| SCHEMBL9015745 | 0.79 | LMNA (0.30) | LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL9143508 | 0.78 | DGKA (0.37) | LMNAKMT2ATDP1 | |
| SCHEMBL25324798 | 0.76 | TSHR (0.30) | — | |
| SCHEMBL3679994 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL27338288 | 0.76 | MIF (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516856-A | IMPROVED PROCESS FOR THE MODIFICATION OF THE MOLECULAR CHAIN OF A POLYMER | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5051531-A | As polymerization catalysts and for crosslinking | ATOCHEM NORTH AMERICA, INC. (US) | 1991-09-24 | — | — | US | disclosed |