Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015599 | 0.94 | CES2 (0.41) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL9015745 | 0.89 | LMNA (0.30) | HSD17B10LMNA | |
| SCHEMBL9015710 | 0.86 | PLA2G4B (0.35) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL9015712 | 0.85 | DGKA (0.44) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL10453272 | 0.81 | DGKA (0.46) | CES2POLBMAPTHSD17B10CES1 | |
| SCHEMBL9015664 | 0.81 | DGKA (0.47) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL9015614 | 0.80 | DGKA (0.46) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL10712716 | 0.79 | DGKA (0.50) | CES2MAPTHSD17B10CES1DGKA | |
| SCHEMBL19118231 | 0.79 | DGKA (0.50) | CES2MAPTHSD17B10CES1DGKA | |
| SCHEMBL4817980 | 0.79 | DGKA (0.50) | CES2MAPTHSD17B10CES1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516856-A | IMPROVED PROCESS FOR THE MODIFICATION OF THE MOLECULAR CHAIN OF A POLYMER | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5051531-A | As polymerization catalysts and for crosslinking | ATOCHEM NORTH AMERICA, INC. (US) | 1991-09-24 | — | — | US | disclosed |