SCHEMBL9015787

SCHEMBL9015787

CCNc1nc(SSc2nc(NCC)nc(N(CC)CC)n2)nc(N(CC)CC)n1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
GAA P10253 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
KDM4E B2RXH2 1/20 0.42
MAPT P10636 4/20 0.40
LMNA P02545 3/20 0.40
HTT P42858 2/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
POLB P06746 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CREBBP Q92793 1/20 0.38
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244239 0.93 L3MBTL1 (0.43) L3MBTL1GAACYP1A2CYP2C19KDM4E
SCHEMBL11328750 0.93 L3MBTL1 (0.43) L3MBTL1GAACYP1A2CYP2C19KDM4E
SCHEMBL9863440 0.86 CA1 (0.41) L3MBTL1GAACYP1A2CYP2C19LMNA
SCHEMBL9849818 0.86 L3MBTL1 (0.47) L3MBTL1GAACYP1A2CYP2C19KDM4E
Hydrochloric Acid SCHEMBL11788350 0.85 L3MBTL1 (0.42) L3MBTL1GAACYP1A2CYP2C19KDM4E
SCHEMBL6716129 0.85 GAA (0.61) L3MBTL1GAACYP1A2CYP2C19KDM4E
SCHEMBL762576 0.85 GAA (0.55) L3MBTL1GAACYP1A2CYP2C19KDM4E
SCHEMBL761988 0.85 GAA (0.61) L3MBTL1GAACYP1A2CYP2C19KDM4E
SCHEMBL9863451 0.83 L3MBTL1 (0.41) L3MBTL1GAACYP1A2CYP2C19KDM4E
SCHEMBL9863554 0.81 L3MBTL1 (0.44) L3MBTL1GAACYP1A2CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3938574-A Vulcanizable rubber mixture for tire treads having improved skid resistance DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-02-17 US claimed
EP-0258676-B1 Process for the preparation of mixtures of sulphur-containing triazine compounds SWAN THOMAS & CO LTD (GB) 1996-12-27 EP disclosed
EP-0347524-B1 Bis(2,4-organylthio-s-triazin-6-yl)polysulphanes, method for their preparation and vulcanisable rubber compositions containing them DEGUSSA (DE) 1995-06-28 EP disclosed
EP-0239816-B1 N,N'-substituted bis-(2,4-diamino-s-triazin-6-yl)-tetrasulphides and their disproportionation products, process for their preparation and their use in vulcanisable rubber mixtures DEGUSSA (DE) 1994-05-11 EP disclosed
US-5206304-A Vulcanizable rubber mixtures containing bis-(2,4-organylthio-triazine-6-yl) polysulfides DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-04-27 US disclosed
US-5037872-A Substituted N-trichloromethyl thiodicarboximides and N,N-substituted bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber FEDERAL REPUBLIC OF GERMANY (DE) 1991-08-06 US disclosed
EP-0347524-A2 Bis(2,4-organylthio-s-triazin-6-yl)polysulphanes, method for their preparation and vulcanisable rubber compositions containing them Thomas Swan and Co. Ltd (GB) 1989-12-27 EP disclosed
US-4837322-A Mixtures of sulfurous triazine compounds DEGUSSA AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
EP-0258676-A2 Process for the preparation of mixtures of sulphur-containing triazine compounds Thomas Swan and Co. Ltd (GB) 1988-03-09 EP disclosed
EP-0240711-A2 Use of substituted N-trichloromethylthiodicarboximides in combination with N,N'-substituted bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber compositions, and such rubber compositions Degussa Aktiengesellschaft (DE) 1987-10-14 EP disclosed
EP-0239816-A2 N,N'-substituted bis-(2,4-diamino-s-triazin-6-yl)-tetrasulphides and their disproportionation products, process for their preparation and their use in vulcanisable rubber mixtures Degussa Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4673741-A HEAT RESISTANCE; CROSSLINKING AND PROMOTING DEGUSSA AG (DE) 1987-06-16 US disclosed
US-4621121-A Vulcanizable mixture containing bis-(2-ethylamino-s-triazin-6-yl)-tetrasulfide DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-11-04 US disclosed
US-4303765-A PEPTIZATION WITH AROMATIC POLYSULFIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed
US-4278587-A HALOALKYLSILANE DEGUSSA AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed
US-4229333-A IN ABSENCE OF ELEMENTAL SULFUR DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-10-21 US disclosed
US-4222915-A Vulcanizable halorubber mixtures DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-09-16 US disclosed
US-4053461-A ELASTOMER VULCANIZATION DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-10-11 US disclosed
US-3968074-A CROSSLINKING ELASTOMERS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-07-06 US disclosed
US-3938574-A Vulcanizable rubber mixture for tire treads having improved skid resistance DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-02-17 US disclosed