SCHEMBL9244239

SCHEMBL9244239

CCNc1nc(SSSSc2nc(NCC)nc(N(CC)CC)n2)nc(N(CC)CC)n1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
CYP1A2 P05177 1/20 0.43
GAA P10253 1/20 0.43
CYP2C19 P33261 1/20 0.43
KDM4E B2RXH2 1/20 0.41
MAPT P10636 5/20 0.39
LMNA P02545 3/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTT P42858 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CREBBP Q92793 1/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11328750 0.97 L3MBTL1 (0.43) L3MBTL1CYP1A2GAACYP2C19KDM4E
SCHEMBL9015787 0.93 L3MBTL1 (0.46) L3MBTL1CYP1A2GAACYP2C19KDM4E
SCHEMBL9334250 0.87 L3MBTL1 (0.41) L3MBTL1CYP1A2GAACYP2C19KDM4E
SCHEMBL9335222 0.87 CA1 (0.39) L3MBTL1CYP1A2GAACYP2C19LMNA
SCHEMBL9333920 0.84 L3MBTL1 (0.39) L3MBTL1CYP1A2GAACYP2C19KDM4E
SCHEMBL9337182 0.84 TP53 (0.40) MAPTTSHRSMN1; SMN2HTTCA1
SCHEMBL9337229 0.84 CRHR1 (0.39) L3MBTL1CYP1A2GAACYP2C19KDM4E
SCHEMBL9849818 0.83 L3MBTL1 (0.47) L3MBTL1CYP1A2GAACYP2C19KDM4E
SCHEMBL9337248 0.82 L3MBTL1 (0.42) L3MBTL1CYP1A2GAACYP2C19KDM4E
Hydrochloric Acid SCHEMBL11788350 0.82 L3MBTL1 (0.42) L3MBTL1CYP1A2GAACYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0239816-B1 N,N'-substituted bis-(2,4-diamino-s-triazin-6-yl)-tetrasulphides and their disproportionation products, process for their preparation and their use in vulcanisable rubber mixtures DEGUSSA (DE) 1994-05-11 EP claimed
EP-0178444-B1 BIS-(2-ETHYLAMINO-4-DIETHYLAMINO-S-TRIAZIN-6-YL)TETRASULFIDE, PROCESS FOR ITS PREPARATION AND USE, AND VULCANISABLE MIXTURES CONTAINING IT Degussa Aktiengesellschaft (DE) 1989-11-08 EP claimed
US-4673741-A HEAT RESISTANCE; CROSSLINKING AND PROMOTING DEGUSSA AG (DE) 1987-06-16 US claimed
US-4621121-A Vulcanizable mixture containing bis-(2-ethylamino-s-triazin-6-yl)-tetrasulfide DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-11-04 US claimed
EP-0347524-B1 Bis(2,4-organylthio-s-triazin-6-yl)polysulphanes, method for their preparation and vulcanisable rubber compositions containing them DEGUSSA (DE) 1995-06-28 EP disclosed
EP-0239816-B1 N,N'-substituted bis-(2,4-diamino-s-triazin-6-yl)-tetrasulphides and their disproportionation products, process for their preparation and their use in vulcanisable rubber mixtures DEGUSSA (DE) 1994-05-11 EP disclosed
CN-1015257-B Preparation method of bis- (2-ethylamino-4-diethylamino-S-triazine-6-yl) tetrasulfide DEGUSSA (DE) 1992-01-01 CN disclosed
CN-1015257-B Preparation method of bis- (2-ethylamino-4-diethylamino-S-triazine-6-yl) tetrasulfide DEGUSSA (DE) 1992-01-01 CN disclosed
US-5037872-A Substituted N-trichloromethyl thiodicarboximides and N,N-substituted bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber FEDERAL REPUBLIC OF GERMANY (DE) 1991-08-06 US disclosed
EP-0427942-A2 Process for the preparation of s-triazine-sulfenimides and their use Degussa Aktiengesellschaft (DE) 1991-05-22 EP disclosed
EP-0347524-A2 Bis(2,4-organylthio-s-triazin-6-yl)polysulphanes, method for their preparation and vulcanisable rubber compositions containing them Thomas Swan and Co. Ltd (GB) 1989-12-27 EP disclosed
EP-0178444-B1 BIS-(2-ETHYLAMINO-4-DIETHYLAMINO-S-TRIAZIN-6-YL)TETRASULFIDE, PROCESS FOR ITS PREPARATION AND USE, AND VULCANISABLE MIXTURES CONTAINING IT Degussa Aktiengesellschaft (DE) 1989-11-08 EP disclosed
US-4673741-A HEAT RESISTANCE; CROSSLINKING AND PROMOTING DEGUSSA AG (DE) 1987-06-16 US disclosed
US-4673741-A HEAT RESISTANCE; CROSSLINKING AND PROMOTING DEGUSSA AG (DE) 1987-06-16 US disclosed
US-4621121-A Vulcanizable mixture containing bis-(2-ethylamino-s-triazin-6-yl)-tetrasulfide DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-11-04 US disclosed
US-4621121-A Vulcanizable mixture containing bis-(2-ethylamino-s-triazin-6-yl)-tetrasulfide DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-11-04 US disclosed
EP-0178444-A2 Bis-(2-ethylamino-4-diethylamino-s-triazin-6-yl)tetrasulfide, process for its preparation and use, and vulcanisable mixtures containing it Degussa Aktiengesellschaft (DE) 1986-04-23 EP disclosed
EP-0178444-A2 Bis-(2-ethylamino-4-diethylamino-s-triazin-6-yl)tetrasulfide, process for its preparation and use, and vulcanisable mixtures containing it Degussa Aktiengesellschaft (DE) 1986-04-23 EP disclosed
EP-0178444-A2 Bis-(2-ethylamino-4-diethylamino-s-triazin-6-yl)tetrasulfide, process for its preparation and use, and vulcanisable mixtures containing it Degussa Aktiengesellschaft (DE) 1986-04-23 EP disclosed
US-4303765-A PEPTIZATION WITH AROMATIC POLYSULFIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed