Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337229 | 0.94 | CRHR1 (0.39) | L3MBTL1CYP1A2GAACYP2C19CRHR1 | |
| SCHEMBL9334250 | 0.84 | L3MBTL1 (0.41) | L3MBTL1CYP1A2GAACYP2C19CRHR1 | |
| SCHEMBL9015787 | 0.83 | L3MBTL1 (0.46) | L3MBTL1CYP1A2GAACYP2C19MAPT | |
| SCHEMBL9015890 | 0.79 | LMNA (0.56) | L3MBTL1CYP1A2GAACYP2C19CRHR1 | |
| SCHEMBL9333911 | 0.79 | CYP1A2 (0.42) | L3MBTL1CYP1A2GAACYP2C19CRHR1 | |
| SCHEMBL9333906 | 0.78 | SLC29A1 (0.43) | CRHR1MAPTLMNASMN1; SMN2SLC29A1 | |
| SCHEMBL9244239 | 0.78 | L3MBTL1 (0.43) | L3MBTL1CYP1A2GAACYP2C19MAPT | |
| SCHEMBL11328750 | 0.78 | L3MBTL1 (0.43) | L3MBTL1CYP1A2GAACYP2C19MAPT | |
| SCHEMBL9863554 | 0.76 | L3MBTL1 (0.44) | L3MBTL1CYP1A2GAACYP2C19MAPT | |
| SCHEMBL6720244 | 0.75 | SLC29A1 (0.51) | CRHR1MAPTSMN1; SMN2SLC29A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037872-A | Substituted N-trichloromethyl thiodicarboximides and N,N-substituted bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber | FEDERAL REPUBLIC OF GERMANY (DE) | 1991-08-06 | — | — | US | disclosed |
| EP-0240711-A2 | Use of substituted N-trichloromethylthiodicarboximides in combination with N,N'-substituted bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber compositions, and such rubber compositions | Degussa Aktiengesellschaft (DE) | 1987-10-14 | — | — | EP | disclosed |