Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.64 |
| ▸ | CES2 | O00748 | 5/20 | 0.64 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28916784 | 0.98 | CES2 (0.65) | CES1CES2FAAHPPARGPPARD | |
| SCHEMBL27974345 | 0.98 | CES2 (0.65) | CES1CES2FAAHPPARGPPARD | |
| SCHEMBL3374395 | 0.93 | CES1 (0.62) | CES1CES2FAAHAKR1B1PPARG | |
| SCHEMBL6739783 | 0.87 | CES2 (0.52) | CES1CES2FAAHTSHRALDH1A1 | |
| SCHEMBL3014656 | 0.84 | FAAH (0.76) | CES1CES2FAAHAKR1B1PPARG | |
| SCHEMBL16060357 | 0.82 | — | — | |
| SCHEMBL7751187 | 0.82 | FAAH (0.79) | CES1CES2FAAHPPARGPPARD | |
| SCHEMBL7752209 | 0.82 | FAAH (0.79) | CES1CES2FAAHPPARGPPARD | |
| SCHEMBL7640125 | 0.82 | FAAH (0.79) | CES1CES2FAAHPPARGPPARD | |
| SCHEMBL1088961 | 0.82 | FAAH (0.79) | CES1CES2FAAHPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578550-B1 | Process for the para-hydroxyalkylation of hydroxylated aromatic compounds | RHONE POULENC CHIMIE (FR) | 1996-12-27 | — | — | EP | claimed |
| US-5430183-A | Para-hydroxyalkylation of hydroxylated aromatic compounds | RHONE-POULENC CHIMIE (FR) | 1995-07-04 | — | — | US | claimed |
| EP-0047693-B1 | PROCESS FOR THE PREPARATION OF HYDROXYARYLGLYOXYLIC ACIDS AND THEIR ALKALI SALTS, AND THEIR USE IN THE PREPARATION OF SODIUM-PARA-HYDROXYPHENYL GLYOXYLATE | SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) | 1984-02-15 | — | — | EP | claimed |
| CN-106029627-B | Method for isolating mandelic compounds in salified form and use thereof for preparing aromatic aldehydes | 罗地亚经营管理公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-106029627-A | Method for separating mandelic compounds in salified form and use of same for preparing aromatic aldehyde | 罗地亚经营管理公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105916834-A | Process for preparing mandelic aromatic compounds and aromatic aldehyde compounds | 罗地亚经营管理公司 | 2016-08-31 | — | — | CN | disclosed |
| US-5430183-A | Para-hydroxyalkylation of hydroxylated aromatic compounds | RHONE-POULENC CHIMIE (FR) | 1995-07-04 | — | — | US | disclosed |
| US-4384137-A | CATALYTIC OXIDATION WITH CUPRIC IONS | SOCIETE FRANCAISE HOECHST (FR) | 1983-05-17 | — | — | US | disclosed |