Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287505 | 0.95 | L3MBTL1 (0.58) | L3MBTL1CHRNB2CHRNA4ALDH1A1HRH3 | |
| Hydrochloric Acid SCHEMBL5578157 | 0.94 | L3MBTL1 (0.56) | L3MBTL1CHRNB2CHRNA4ALDH1A1HRH3 | |
| SCHEMBL9527993 | 0.81 | L3MBTL1 (0.68) | L3MBTL1HRH3ACHEMAPK1TDP1 | |
| SCHEMBL10754118 | 0.81 | ALDH1A1 (0.53) | CHRNB2CHRNA4ALDH1A1MAPTMEN1 | |
| SCHEMBL596252 | 0.80 | L3MBTL1 (0.96) | L3MBTL1HRH3ACHEMEN1GAA | |
| SCHEMBL7269112 | 0.79 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1HRH3MAPTACHE | |
| SCHEMBL1626076 | 0.79 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1HRH3MAPTACHE | |
| SCHEMBL9212361 | 0.79 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1HRH3MAPTACHE | |
| SCHEMBL610772 | 0.79 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1HRH3MAPTACHE | |
| Hydrochloric Acid SCHEMBL27853152 | 0.79 | L3MBTL1 (0.93) | L3MBTL1HRH3ACHEMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530134-A | Synthesis of anabaseine, salts and derivatives thereof | SYNPHAR LABORATORIES INC. (CA) | 1996-06-25 | — | — | US | disclosed |