Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016165 | 0.99 | KDM4E (0.50) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9016170 | 0.97 | MEN1 (0.49) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL10168711 | 0.90 | KMT2A (0.52) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL29287392 | 0.80 | MCL1 (0.57) | MAPTL3MBTL1ALDH1A1HTTGAA | |
| SCHEMBL10354365 | 0.78 | MCL1 (0.59) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL1720721 | 0.77 | MCL1 (0.67) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7239882 | 0.75 | L3MBTL1 (0.50) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL31236155 | 0.75 | MCL1 (0.60) | MAPTL3MBTL1ALDH1A1HTTGAA | |
| SCHEMBL9435566 | 0.74 | L3MBTL1 (0.49) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL29588286 | 0.74 | SLC18A3 (0.45) | KDM4EMAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530134-A | Synthesis of anabaseine, salts and derivatives thereof | SYNPHAR LABORATORIES INC. (CA) | 1996-06-25 | — | — | US | claimed |
| JP-8176109-A | — | — | None | — | — | JP | disclosed |
| JP-H08176109-A | SYNTHESIS OF ANABASEINE, SALT AND DERIVATIVE THEREOF, AND PRODUCT AND INTERMEDIATE | SYNPHAR LAB INC | 1996-07-09 | — | — | JP | disclosed |
| US-5530134-A | Synthesis of anabaseine, salts and derivatives thereof | SYNPHAR LABORATORIES INC. (CA) | 1996-06-25 | — | — | US | disclosed |
| US-5530134-A | Synthesis of anabaseine, salts and derivatives thereof | SYNPHAR LABORATORIES INC. (CA) | 1996-06-25 | — | — | US | disclosed |