Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239882 | 0.99 | L3MBTL1 (0.50) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29365856 | 0.82 | MCL1 (0.56) | L3MBTL1KDM4EMEN1KMT2APOLB | |
| SCHEMBL10354365 | 0.78 | MCL1 (0.59) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1720721 | 0.77 | MCL1 (0.67) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29516338 | 0.76 | MCL1 (0.57) | L3MBTL1KDM4EMEN1KMT2APOLB | |
| SCHEMBL9016165 | 0.75 | KDM4E (0.50) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9016167 | 0.74 | KDM4E (0.49) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7241178 | 0.74 | CHRNB2 (0.48) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9016170 | 0.74 | MEN1 (0.49) | L3MBTL1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8245353 | 0.73 | SLC18A3 (0.56) | L3MBTL1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573568-A4 | USE OF NICOTINIC ANALOGS FOR TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM | UNIV FLORIDA (US) | 1994-09-21 | — | — | EP | claimed |
| EP-0573568-A1 | USE OF NICOTINIC ANALOGS FOR TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1993-12-15 | — | — | EP | claimed |
| WO-1992015306-A1 | USE OF NICOTINIC ANALOGS FOR TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM | UNIVERSITY OF FLORIDA (US) | 1992-09-17 | — | — | WO | claimed |
| US-9567315-B1 | Method for synthesis of 4-OH substituted anabaseine derivative | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2017-02-14 | — | — | US | disclosed |