Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 2/20 | 0.59 |
| ▸ | RARG | P13631 | 2/20 | 0.59 |
| ▸ | RARA | P10276 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016206 | 1.00 | ALOX5 (0.59) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL20839001 | 0.91 | ALOX5 (0.60) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL20839002 | 0.91 | ALOX5 (0.60) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL703377 | 0.88 | RARB (0.60) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL703376 | 0.88 | RARB (0.60) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL9202781 | 0.88 | RARB (0.60) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL23587933 | 0.85 | ALOX15 (0.64) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL9016180 | 0.85 | ALOX15 (0.60) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL1105238 | 0.85 | ALOX15 (0.60) | ALOX5ALOX15RARBRARGRARA | |
| SCHEMBL5595508 | 0.85 | ALOX15 (0.60) | ALOX5ALOX15RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403945-B1 | Cycloaliphatic carbinols and their use as starting materials for the preparation of furan derivatives | FIRMENICH & CIE (CH) | 1996-12-18 | — | — | EP | disclosed |
| US-5155239-A | Preparation of polycyclic ethers | FIRMENICH S.A. (CH) | 1992-10-13 | — | — | US | disclosed |
| US-5155238-A | Acidic cyclization of polyunsaturated, acyclic alcohol or protected alcohol; stereospecific; organoleptic | FIRMENICH S.A. (CH) | 1992-10-13 | — | — | US | disclosed |
| US-5077417-A | Acidifying, cyclizing a polyunsaturated alicyclic alcohol or protected hydroxy group | FIRMENICH SA (CH) | 1991-12-31 | — | — | US | disclosed |
| EP-0403945-A2 | Cycloaliphatic carbinols and their use as starting materials for the preparation of furan derivatives | FIRMENICH SA (CH) | 1990-12-27 | — | — | EP | disclosed |