Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016255 | 0.86 | L3MBTL1 (0.52) | KMT2AKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9016259 | 0.82 | KMT2A (0.62) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL9016231 | 0.71 | MEN1 (0.66) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL9212854 | 0.71 | CYP3A4 (0.76) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL9016243 | 0.70 | KMT2A (0.66) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL23391645 | 0.70 | BACE1 (0.45) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL29715998 | 0.70 | BACE1 (0.45) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL7430428 | 0.70 | CYP1A2 (1.00) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL1586895 | 0.70 | NPC1 (0.62) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30465890 | 0.70 | NPC1 (0.62) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482964-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | disclosed |