Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016244 | 0.87 | ADRB2 (0.63) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016222 | 0.85 | KCNH2 (0.61) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016252 | 0.85 | KCNH2 (0.61) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016229 | 0.84 | HTR2B (0.60) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016210 | 0.83 | KCNH2 (0.59) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016253 | 0.83 | KCNH2 (0.59) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016250 | 0.83 | KCNH2 (0.59) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016256 | 0.83 | ADRB2 (0.58) | MEN1KMT2AADRB2ADRB1HTR1A | |
| SCHEMBL9016243 | 0.82 | KMT2A (0.66) | MEN1KMT2AKCNH2KDM4EALDH1A1 | |
| SCHEMBL9016221 | 0.82 | KCNH2 (0.57) | MEN1KMT2AADRB2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482964-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | disclosed |