Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531434 | 0.89 | GRM2 (0.52) | GRM2L3MBTL1KMT2AMEN1DDB1 | |
| SCHEMBL4519506 | 0.88 | GRM2 (0.51) | GRM2L3MBTL1KMT2AMEN1DDB1 | |
| SCHEMBL13946692 | 0.83 | SMN1; SMN2 (0.60) | GRM2KMT2AMEN1PIK3CDPOLB | |
| SCHEMBL2583214 | 0.78 | PIK3CD (0.44) | GRM2KMT2AMEN1PIK3CDPOLB | |
| SCHEMBL2794226 | 0.77 | L3MBTL1 (0.59) | L3MBTL1KMT2AMEN1DDB1CRBN | |
| SCHEMBL6885751 | 0.74 | GRIN1 (0.47) | GRM2PIK3CDFAAHNAAA | |
| SCHEMBL2534297 | 0.74 | GRM2 (0.51) | GRM2PIK3CD | |
| SCHEMBL16488375 | 0.74 | DDB1 (0.47) | L3MBTL1KMT2AMEN1DDB1CRBN | |
| SCHEMBL4619569 | 0.74 | SMN1; SMN2 (0.71) | L3MBTL1KMT2AMEN1DDB1CRBN | |
| SCHEMBL2581182 | 0.73 | ACHE (0.48) | KMT2AMEN1POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632022-B1 | Process for the preparation of amino-substituted thioethers | BAYER AG (DE) | 1996-12-27 | — | — | EP | disclosed |
| US-5410081-A | Process for the preparation of amino-substituted thioethers | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| EP-0632022-A2 | Process for the preparation of amino-substituted thioethers | BAYER AG (DE) | 1995-01-04 | — | — | EP | disclosed |