Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13463537 | 0.95 | SIRT2 (0.41) | PIK3CDGRM2SIRT2SIRT1MAPT | |
| SCHEMBL20695806 | 0.79 | KDM4E (0.44) | GRM2MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9016265 | 0.78 | GRM2 (0.56) | PIK3CDGRM2MAPTKDM4EALDH1A1 | |
| SCHEMBL2581182 | 0.77 | ACHE (0.48) | SIRT2SIRT1KDM4EALDH1A1POLB | |
| SCHEMBL27834661 | 0.77 | MAPT (0.68) | SIRT2SIRT1MAPTKDM4EALDH1A1 | |
| SCHEMBL14537170 | 0.76 | MAPK1 (0.56) | SIRT2SIRT1MAPTALDH1A1POLB | |
| SCHEMBL2578048 | 0.76 | SIRT2 (0.41) | GRM2SIRT2SIRT1MAPTKDM4E | |
| SCHEMBL14403257 | 0.73 | ALDH1A1 (0.67) | SIRT2SIRT1MAPTKDM4EALDH1A1 | |
| SCHEMBL514643 | 0.73 | SIRT2 (0.42) | GRM2SIRT2SIRT1PER2CRY2 | |
| SCHEMBL5584770 | 0.72 | MPO (0.51) | GRM2SIRT2SIRT1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048825-B2 | Haloalkylsulfonanilide derivatives or salt thereof, herbicide comprising the derivatives as active ingredient, and use of the herbicide | NIHON NOHYAKU CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20100016164-A1 | HALOALKYLSULFONANILIDE DERIVATIVES OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVES AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2085392-A1 | HALOALKYLSULFONANILIDE DERIVATIVE OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | Nihon Nohyaku CO., LTD. (JP) | 2009-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016164-A1 | HALOALKYLSULFONANILIDE DERIVATIVES OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVES AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | HDHD5, CBR3, DHRS9 | PIK3CD 1776/4885GRM2 1887/4885SIRT2 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.