SCHEMBL9016291

SCHEMBL9016291

CCCc1ccc2nc(S)sc2c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.49
NPC1 O15118 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CASP3 P42574 9/20 0.40
SENP8 Q96LD8 9/20 0.40
SENP7 Q9BQF6 9/20 0.40
SENP6 Q9GZR1 9/20 0.40
PCSK9 Q8NBP7 1/20 0.40
APP P05067 2/20 0.38
MAPT P10636 1/20 0.38
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
HRH1 P35367 1/20 0.36
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10383951 0.90 CASP3 (0.49) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL10383965 0.88 CASP3 (0.45) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL14859131 0.88 CASP3 (0.45) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL10358903 0.87 HSD17B10 (0.45) RAB9ANPC1SMN1; SMN2MAPTCNR1
SCHEMBL917810 0.86 RAB9A (0.65) RAB9ANPC1SMN1; SMN2APPMAPT
SCHEMBL14557082 0.86 RAB9A (0.44) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL6046313 0.83 RAB9A (0.41) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL13273315 0.81 SMN1; SMN2 (0.54) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL5545581 0.80 RAB9A (0.49) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL5545588 0.80 RAB9A (0.49) RAB9ANPC1SMN1; SMN2CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7455959-B2 Photographic element containing a speed-enhancing compound EASTMAN KODAK COMPANY (US) 2008-11-25 US disclosed
US-20080248433-A1 PHOTOGRAPHIC ELEMENT CONTAINING A SPEED-ENHANCING COMPOUND NPEC INC. 2008-10-09 US disclosed
US-7354701-B2 Photographic element with speed-enhancing compound EASTMAN KODAK COMPANY (US) 2008-04-08 US disclosed
US-20070128560-A1 Photographic element with speed-enhancing compound EASTMAN KODAK COMPANY 2007-06-07 US disclosed
US-5505310-A FLOTATION OF SULFIDES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1996-04-09 US disclosed
EP-0615467-B1 2-MERCAPTO-BENZOXAZOLE DERIVATIVES AS COLLECTORS FOR THE SELECTIVE FLOTATION OF METAL ORES CONSIGLIO NAZIONALE RICERCHE (IT) 1995-08-23 EP disclosed
EP-0615467-A1 2-MERCAPTO-BENZOXAZOLE DERIVATIVES AS COLLECTORS FOR THE SELECTIVE FLOTATION OF METAL ORES. CONSIGLIO NAZIONALE RICERCHE (IT) 1994-09-21 EP disclosed
WO-1993010903-A1 2-MERCAPTO-BENZOXAZOLE DERIVATIVES AS COLLECTORS FOR THE SELECTIVE FLOTATION OF METAL ORES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1993-06-10 WO disclosed