Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2081159 | 0.71 | GAA (0.39) | ALDH1A1KDM4EKMT2AHTTRXFP1 | |
| SCHEMBL28986134 | 0.71 | TRPM8 (0.47) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL8701288 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL9274056 | 0.70 | GAA (0.65) | ALDH1A1KDM4EHPGDLMNAGAA | |
| SCHEMBL9846144 | 0.69 | PDE3B (0.36) | ALDH1A1KDM4EKMT2AHPGDHTT | |
| SCHEMBL27701369 | 0.69 | APAF1 (0.40) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL9016296 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHTTHSD17B10 | |
| SCHEMBL10881610 | 0.67 | SMN1; SMN2 (0.47) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL1927016 | 0.67 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AHTTTSHR | |
| SCHEMBL380050 | 0.67 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |