Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 5/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058202 | 0.94 | FAAH (0.47) | TAAR1NPC1GAARAB9AFAAH | |
| SCHEMBL9016298 | 0.92 | BRD4 (0.47) | TAAR1NPC1GAARAB9AFAAH | |
| SCHEMBL8701292 | 0.89 | ALDH1A1 (0.43) | TAAR1NPC1GAARAB9AFAAH | |
| SCHEMBL6953240 | 0.81 | KMT2A (0.46) | NPC1GAARAB9ATRPV1 | |
| SCHEMBL9058102 | 0.80 | FAAH (0.43) | FAAHBRD4 | |
| SCHEMBL8699410 | 0.79 | MAPT (0.40) | NPC1GAARAB9A | |
| SCHEMBL6966654 | 0.76 | ALDH1A1 (0.43) | NPC1GAARAB9AFAAHTRPV1 | |
| SCHEMBL8699180 | 0.76 | HPGD (0.41) | GAA | |
| SCHEMBL8699066 | 0.74 | RAB9A (0.44) | NPC1GAARAB9AFAAHTRPV1 | |
| SCHEMBL8703454 | 0.74 | MAPK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |