Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916315 | 0.85 | TSHR (0.49) | HTTMEN1KMT2AIDO1TSHR | |
| SCHEMBL916701 | 0.84 | KDM4E (0.36) | ALDH1A1HTTEPHX2MAOBTSHR | |
| SCHEMBL5250121 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL642703 | 0.82 | FDPS (0.42) | ALDH1A1TSHRHPGD | |
| SCHEMBL3086597 | 0.82 | IDO1 (0.34) | ALDH1A1KMT2AIDO1TSHR | |
| SCHEMBL2008230 | 0.82 | EPHX2 (0.36) | EPHX2IDO1TSHRHPGD | |
| SCHEMBL9386757 | 0.80 | SRC (0.39) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL915190 | 0.80 | FOLH1 (0.40) | ALDH1A1HTTMEN1KMT2ATSHR | |
| SCHEMBL8958928 | 0.80 | HSD17B10 (0.43) | ALDH1A1HTTNPC1SLC6A2SLC6A4 | |
| SCHEMBL9273637 | 0.79 | TSHR (0.39) | ALDH1A1NPC1SMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274466-A1 | PROCESS FOR THE PREPARATION OF TETRACYCLIC DERIVATIVES AND INTERMEDIATE PRODUCTS USED IN THE PROCESS | ALPHORA RESEARCH INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| EP-2621898-A1 | PROCESS FOR THE PREPARATION OF TETRACYCLIC DERIVATIVES AND INTERMEDIATE PRODUCTS USED IN THE PROCESS | Alphora Research Inc. (CA) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012040845-A1 | PROCESS FOR THE PREPARATION OF TETRACYCLIC DERIVATIVES AND INTERMEDIATE PRODUCTS USED IN THE PROCESS | ALPHORA RESEARCH INC. (CA) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274466-A1 | PROCESS FOR THE PREPARATION OF TETRACYCLIC DERIVATIVES AND INTERMEDIATE PRODUCTS USED IN THE PROCESS | NISCH, SSRP1, UMPS | ALDH1A1 261/4885HTT 1828/4885NPC1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.