Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016828 | 0.82 | SLC6A3 (0.51) | ALDH1A1GAASLC6A3FFAR1SLC6A4 | |
| SCHEMBL2577670 | 0.77 | SLC6A3 (0.65) | ALDH1A1SLC6A3FFAR1SLC6A4 | |
| SCHEMBL16011837 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL6074896 | 0.77 | SLC6A3 (0.65) | SLC6A3SLC6A4 | |
| SCHEMBL9016798 | 0.77 | SLC6A3 (0.46) | SLC6A3 | |
| SCHEMBL9016821 | 0.76 | FFAR1 (0.47) | L3MBTL1SLC6A3FFAR1SLC6A4CNR2 | |
| Hydrochloric Acid SCHEMBL2577794 | 0.76 | SLC6A3 (0.62) | ALDH1A1SLC6A3FFAR1SLC6A4 | |
| SCHEMBL10692480 | 0.74 | ALDH1A1 (0.71) | ALDH1A1GAAL3MBTL1FFAR1CNR2 | |
| SCHEMBL9016806 | 0.73 | SLC6A3 (0.55) | SLC6A3FFAR1SLC6A4 | |
| SCHEMBL13644998 | 0.73 | FFAR1 (0.59) | ALDH1A1GAAL3MBTL1FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571825-A | Method of selectively inhibiting prostaglandin G/H synthase-2 | WARNER-LAMBERT COMPANY (US) | 1996-11-05 | — | — | US | disclosed |