Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.53 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016960 | 1.00 | OPRM1 (0.53) | OPRM1OPRK1OPRD1G6PC1KDM4E | |
| SCHEMBL9016990 | 0.95 | OPRM1 (0.51) | OPRM1OPRK1OPRD1G6PC1KDM4E | |
| SCHEMBL9016988 | 0.95 | OPRM1 (0.51) | OPRM1OPRK1OPRD1G6PC1KDM4E | |
| SCHEMBL5722096 | 0.88 | OPRM1 (0.61) | OPRM1OPRK1OPRD1G6PC1KDM4E | |
| SCHEMBL12126132 | 0.82 | OPRM1 (0.54) | OPRM1OPRK1OPRD1KDM4EHSD17B10 | |
| SCHEMBL12126130 | 0.80 | OPRM1 (0.56) | OPRM1OPRK1OPRD1KDM4EHSD17B10 | |
| SCHEMBL12049804 | 0.79 | NR1D1 (0.48) | OPRM1OPRK1OPRD1HDAC1HDAC6 | |
| SCHEMBL10039132 | 0.78 | OPRM1 (0.54) | OPRM1OPRK1OPRD1KDM4EHSD17B10 | |
| SCHEMBL7721337 | 0.78 | OPRM1 (0.50) | OPRM1OPRK1OPRD1KDM4EHSD17B10 | |
| SCHEMBL30093246 | 0.77 | OPRM1 (0.57) | OPRM1OPRK1OPRD1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | claimed |
| US-5492954-A | STABILIZE LUBRICANTS AND SYNTHETIC POLYMERS AGAINST THE DELETERIOUS EFFECTS OF OXYGEN AND HEAT | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| US-5391808-A | Lubricant and synthetic polymer additives for heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0585202-A1 | N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers | CIBA-GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5283367-A | Antioxidants for lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| US-5240976-A | For automobile, wire and cable uses | CIBA-GEIGY CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | disclosed |