SCHEMBL9016970

SCHEMBL9016970

CC(C=CCN(Cc1ccccc1)c1cccc2ccccc12)N(Cc1ccccc1)c1cccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD2 O60906 1/20 0.37
SIGMAR1 Q99720 5/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KMT2A Q03164 2/20 0.34
NR3C1 P04150 2/20 0.34
HTR1D P28221 1/20 0.34
HTR1B P28222 1/20 0.34
NR1I2 O75469 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2C P18825 1/20 0.34
CNR1 P21554 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2A P28223 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34
OPRK1 P41145 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
EBP Q15125 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016973 1.00 SMPD2 (0.37) SMPD2SIGMAR1L3MBTL1KMT2ANR3C1
SCHEMBL9702215 0.83 L3MBTL1 (0.40) SMPD2SIGMAR1L3MBTL1KMT2AHTR1D
SCHEMBL9702212 0.83 L3MBTL1 (0.40) SMPD2SIGMAR1L3MBTL1KMT2AHTR1D
SCHEMBL27935369 0.77 PSEN1 (0.45) SIGMAR1L3MBTL1KMT2ANR3C1HTR1D
SCHEMBL6541752 0.75 L3MBTL1 (0.45) SIGMAR1L3MBTL1KMT2ANR3C1HTR1D
SCHEMBL2343211 0.72 TSHR (0.59) SIGMAR1L3MBTL1KMT2ANR3C1HTR1D
Hydrochloric Acid SCHEMBL3792219 0.71 TSHR (0.58) SIGMAR1L3MBTL1KMT2ANR3C1HTR1D
SCHEMBL30966945 0.66 SIGMAR1 (0.50) SIGMAR1L3MBTL1KMT2AHTR1DHTR1B
SCHEMBL2865598 0.66 SIGMAR1 (0.50) SIGMAR1L3MBTL1KMT2AHTR1DHTR1B
SCHEMBL29657743 0.65 SIGMAR1 (0.54) SIGMAR1L3MBTL1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492954-A STABILIZE LUBRICANTS AND SYNTHETIC POLYMERS AGAINST THE DELETERIOUS EFFECTS OF OXYGEN AND HEAT CIBA-GEIGY CORPORATION (US) 1996-02-20 US disclosed
US-5391808-A Lubricant and synthetic polymer additives for heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1995-02-21 US disclosed
EP-0585202-A1 N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers CIBA-GEIGY AG (CH) 1994-03-02 EP disclosed
US-5283367-A Antioxidants for lubricants and polymers CIBA-GEIGY CORPORATION (US) 1994-02-01 US disclosed
US-5240976-A For automobile, wire and cable uses CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
EP-0514333-A2 Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-19 EP disclosed